Payul,
In some of my earlier guitars, I slanted the whole bridge just slightly, so that there is a little more compensation on the bass strings, and less on the treble side. I did away with that practice, as I observed more and more guitars that did not seem to be "out of tune" and had no extra clearance at the bass strings. Providing extra distance/compensation for the bass strings is more critical with the steel stringed guitars. The reason for that is because the thickness of the core material of steel string
impacts its flexibility, and in turn, affects the required compensation.
On a 650 scale length, it is customary to place the bridge saddle contact point at somewhere around 651--652mms from the nut. Then again, I've seen variances there.
"In-tune" or "out of tune" are less than straigh-forward when you begin to look at the issues closely. Standards have changed over the years. Many historic stringed instruments were built to the "rule of 18" method. Now, a constant of 17.817 is used to determine fret positions.
I am also quite fascinated and amused by the subject of psycho-acoustics. If beauty is in the eye of the beholder, then I can perhaps stretch this truism to state that harmonious sound is in the ear of the listener. Cultural sensibilities, one's own hearing, volume level, presence or absence of harmonics, all affect our pitch perception. Mathematically-perfect tuning, I concluded, is pretty much unattainable in guitars. In fact, I'd say that most analog instruments played by humans fail strictly-mathematical accuracy standards. Yet, we've been making music, singing ballads, sharing joys and sorrows, wooing our lovers, and entertaining each other since time immemorial.
If you'd like to dig-into some pithier content, check this article right here:
http://liutaiomottola.com/formulae/fret.htm